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Anatomy Exam 3 · Class of 2028

Blood Flow & Vasculature Guide

The arterial supply, venous drainage, and (where the lecture specifies it) lymphatic drainage for every organ across Endocrine, GI, Female Reproductive, Male Reproductive, and Nephrology/Urinary — plus the special sequential "flow chains" (nephron blood flow, hepatic portal system, hypophyseal portal system) worth memorizing as a single path.

How to read this: each table gives arterial supply (where blood comes from) and venous drainage (where it goes to) per structure. Highlighted flow boxes spell out a specific named sequence exactly as it's taught — those are worth memorizing in order.

Endocrine System

Hypophyseal portal system (pituitary) Superior hypophyseal artery → capillary plexus at the median eminence → hypophyseal portal veins → second capillary bed in the adenohypophysis (anterior lobe) — the anterior pituitary receives portal blood, carrying hypothalamic releasing hormones directly to it. The neurohypophysis (posterior lobe), by contrast, is supplied directly by the inferior hypophyseal artery and receives ordinary arterial blood.
StructureArterial supplyVenous drainageLymphatic drainage
Thyroid gland Superior thyroid a. (from external carotid a.) to the apex; inferior thyroid a. (from the thyrocervical trunk of the subclavian a.) related to the recurrent laryngeal nerve; rare thyroidea ima a. variant to the isthmus (arch of aorta or brachiocephalic a.) Superior & middle thyroid veins → internal jugular vein; inferior thyroid vein → brachiocephalic vein Paratracheal nodes and deep cervical nodes (inferior to the omohyoid m.), via vessels in the interlobular connective tissue → thoracic duct & right lymphatic duct
Parathyroid glands Share the same blood, lymphatic, and nerve supply as the thyroid gland (superior/inferior thyroid vessels) — they aren't given their own separate supply.
Pituitary gland Superior hypophyseal a. (to adenohypophysis, via portal system) and inferior hypophyseal a. (directly to neurohypophysis) — see flow box above Hypophyseal veins → dural venous sinuses (cavernous sinus is directly adjacent on either side of the gland) —
Pancreas (head) Superior pancreaticoduodenal a. (from the gastroduodenal a., a common hepatic a. branch) + inferior pancreaticoduodenal a. (from the SMA) — each splits into anterior/posterior branches Corresponding pancreaticoduodenal veins → SMV / portal vein Follows the arterial supply to pancreaticosplenic/celiac nodes → ultimately the cisterna chyli
Pancreas (body & tail) Splenic a. (celiac trunk branch) — runs right to left along the upper margin of the body/tail, giving pancreatic branches Splenic v. (posterior surface, parallel to the artery) → joins SMV & IMV → portal vein
Adrenal (suprarenal) glands Triple supply: superior suprarenal a. (from the inferior phrenic a.), middle suprarenal a. (directly off the abdominal aorta), inferior suprarenal a. (from the renal a.) Asymmetric: right suprarenal vein → IVC directly; left suprarenal vein → left renal vein first —

Gastrointestinal Tract I & II

Hepatic portal system Splenic vein + superior mesenteric vein (SMV) unite → hepatic portal vein → enters the liver at the porta hepatis (as part of the portal triad with the hepatic artery & bile duct) → hepatic sinusoids → central vein of each lobule → hepatic veins → IVC. The portal vein supplies the majority of the liver's blood (nutrient-rich, needs metabolic processing); the hepatic artery supplies only ~15% but is the liver's true oxygen source.
StructureArterial supplyVenous drainageLymphatic drainage
Esophagus (abdominal) Inferior thyroid a. (thyrocervical trunk), branches of the descending thoracic aorta, left gastric a. (celiac trunk), and the left inferior phrenic a. (abdominal aorta) Both the azygos vein (systemic) and the left gastric vein (portal, via the portal vein) — a classic portosystemic anastomosis site Both thoracic (mediastinal) nodes and abdominal (celiac) lymphatics
Stomach, duodenum (proximal), liver, spleen, pancreas (foregut) Celiac trunk (off the aorta at the aortic hiatus) → left gastric a. (lesser curvature), splenic a. (pancreas, spleen), common hepatic a. → proper hepatic a. (right/left hepatic, cystic) + gastroduodenal a. (supraduodenal, right gastric) Left/right gastric veins → portal vein directly or via splenic/SMV confluence; splenic vein → portal vein Celiac nodes → cisterna chyli
Jejunum, ileum, cecum, appendix, ascending & proximal transverse colon (midgut) Superior mesenteric artery (SMA) — unpaired aortic branch Superior mesenteric vein (SMV) → joins splenic vein → portal vein Superior mesenteric nodes → cisterna chyli
Distal transverse, descending & sigmoid colon, rectum (hindgut) Inferior mesenteric artery (IMA) — unpaired aortic branch Inferior mesenteric vein → typically joins the splenic vein → portal vein Inferior mesenteric nodes → cisterna chyli
Liver Triple blood supply: portal vein (majority of flow, nutrient-rich, needs processing) + hepatic artery (~15% of flow, "biliary artery," supplies bile ducts) → sinusoids → central vein → hepatic veins → IVC. See flow box above.
Spleen Splenic a. (celiac trunk branch, runs along the pancreas) Splenic vein → joins SMV to help form the portal vein —
Inferior vena cava (IVC) Formed by the union of the common iliac veins; receives (ascending) lumbar veins, renal veins, right gonadal & right suprarenal veins directly, hepatic veins, and inferior phrenic veins. Left gonadal/suprarenal veins drain into the left renal vein first, not directly into the IVC.

Female Reproductive System

StructureArterial supplyVenous drainageLymphatic drainage
Ovary Ovarian a. — direct branch of the abdominal aorta, enters via the suspensory ligament and sends branches through the mesovarium Via the pampiniform plexus: right ovarian vein → IVC directly; left ovarian vein → left renal vein first Follows the ovarian vessels up to the lumbar (para-aortic) nodes
Uterus Uterine a. (from the internal iliac a.) anastomosing with the ovarian a. Uterine venous plexus → internal iliac veins Mainly internal/external iliac and lumbar nodes (varies by uterine region)
Uterine (fallopian) tubes Ovarian a. and uterine a. (anastomotic supply, matching their position between ovary and uterus) Ovarian and uterine venous routes Lumbar nodes (follows the ovarian vessels)
Vagina Uterine a., vaginal a., and pudendal a. branches Vaginal venous plexus → internal iliac veins By thirds: superior third → internal/external iliac nodes; middle third → internal iliac nodes; inferior third → sacral/common iliac nodes and superficial inguinal nodes
Breast (medial quadrants) Perforating branches (2nd, 3rd, 4th) of the internal thoracic a. + anterior intercostal a. branches Veins follow the corresponding arteries Mostly to the axilla — pectoral (anterior) nodes first (drains most of the breast), then subscapular (posterior), lateral, and central nodes, up to the infra-/supraclavicular nodes; some drainage also crosses to the opposite side
Breast (lateral quadrants) Pectoral branches of the thoracoacromial a. (off the axillary a.) + the external mammary branch of the lateral thoracic a. Veins follow the corresponding arteries

Male Reproductive System

StructureArterial supplyVenous drainageLymphatic / nerve notes
Testis Testicular a. — direct branch of the abdominal aorta, travels the length of the spermatic cord Via the pampiniform plexus → testicular vein: right → IVC directly; left → left renal vein first (mirrors the ovarian pattern) Ilioinguinal & genitofemoral nerves also run in the spermatic cord alongside the vessels
Ductus deferens Deferential a. — a separate named vessel of the spermatic cord (distinct from the testicular a.) Small veins accompanying the deferential artery —
Scrotum Internal pudendal a. (branch of the internal iliac a.), external pudendal a. (branch of the femoral a.), and inferior epigastric a. (branch of the external iliac a.) Corresponding pudendal/epigastric veins Sensory/motor via the hypogastric plexus, ilioinguinal, genitofemoral, and pudendal nerves
Penis Internal pudendal a. branches: deep artery of the penis (runs centrally through each corpus cavernosum) and the dorsal artery (superficial, alongside the dorsal vein & nerve) Dorsal vein (superficial) and deep venous channels from the corpora cavernosa/spongiosum —

Nephrology / Urinary System

Renal blood flow (the classic nephron pathway) Aorta → renal artery → segmental arteries → lobar arteries → interlobar arteries → arcuate artery → interlobular artery → afferent arteriole → glomerulus (filtration) → efferent arteriole → peritubular capillaries or vasa recta → interlobular vein → arcuate vein → interlobar vein → renal vein → IVC.
StructureArterial supplyVenous drainageNotes
Kidney Renal a. — direct branch of the abdominal aorta; the renal plexus (autonomics) accompanies it and enters at the hilum Renal vein → IVC. Left renal vein additionally receives the left gonadal vein (which has no direct IVC route) See the full nephron flow-chain above — this is the pathway worth memorizing step by step
Ureter Segmental branches from the renal a., abdominal aorta, gonadal a., and (distally) the internal iliac a., depending on level Corresponding segmental veins Sensory: T12–L2 nerve roots (extremely pain-sensitive); parasympathetic via pelvic splanchnic nerves. Crosses anterior to the common iliac artery and passes deep/inferior to the testicular or ovarian vessels ("water under the bridge")
Urinary bladder Aorta → common iliac → internal iliac → anterior division → superior & inferior vesical arteries Vesical venous plexus → internal iliac veins → IVC Detrusor muscle innervation involves the hypogastric nerve (sympathetic) and pelvic nerve (parasympathetic); external urethral sphincter via the pudendal nerve (voluntary)