Lecture 5 of Microbiology — Host Defenses: Nonspecific Mechanisms. Thirty questions, every one cited to the slide it came from. This is the largest lecture of the block by some distance: 93 slides against eleven instructional objectives, where Lectures 1 to 4 carry three or four each. The selection is spread deliberately across all eleven rather than letting the big topics crowd out the small ones — complement alone could have filled a set. Covers the three lines of defense; the physical, chemical, microbiological and genetic barriers of the first line; normal flora; the plasma proteins that limit infection, including defensins and the pentraxins; the acute-phase response; pattern recognition and the PAMP against DAMP distinction; inflammation from the inflammasome through extravasation; the mechanism of fever and its beneficial effects; the complement system end to end, from the thioester bond to the membrane attack complex and the regulators that keep it off your own cells; the three interferons; the leukocyte classes with their percentages and the differential white count; phagocytosis and the respiratory burst; and natural killer cells.
Answers reveal only after you choose. Your score and a breakdown by objective appear at the end, with a review of everything you missed.