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Calcium Channel Blockers

Pharmacology I · Exam 2 · Antihypertensives
16 questions

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One distinction organizes the whole class: only diltiazem and verapamil act on the heart, slowing the rate and atrioventricular conduction, so only they treat supraventricular tachycardia — and their bradycardia, heart block and worsening heart failure follow from the same action. Dihydropyridines act on vessels, so their problems are reflex tachycardia and edema. The non-dihydropyridines also inhibit CYP3A4, which raises three statins. What these do and do not ask. Indications, adverse effects, contraindications and patient education are in, weighted above mechanism. Doses are out, so nothing here turns on a milligram, which is why the sets run 14 to 18 rather than the usual 30. Diuretics belong to a later exam and appear only as the add-on step of the treatment algorithm. Every option carries its own reason, correct and incorrect alike.

DihydropyridinesNon-dihydropyridinesNodal effectsCYP3A4Contraindications

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