Two drug classes that block the same system at different points, and the differences that follow. ACE (angiotensin-converting enzyme) inhibitors also stop bradykinin being broken down, which is where the dry cough and angioedema come from and why an angiotensin receptor blocker is the switch. Both classes raise potassium — know who is at risk — and both are avoided in the second and third trimesters. Then the algorithm: what to start for a given comorbidity, and what to add next. What these do and do not ask. Indications, adverse effects, contraindications and patient education are in, weighted above mechanism. Doses are out, so nothing here turns on a milligram, which is why the sets run 14 to 18 rather than the usual 30. Diuretics belong to a later exam and appear only as the add-on step of the treatment algorithm. Every option carries its own reason, correct and incorrect alike.
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